The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis
https://doi.org/10.21518/2079-701X-2016-2-100-101
Abstract
The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function
About the Authors
N. R. Karakashian
First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
E. I. Manukhina
First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
M. A. Gevorgyan
First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
I. B. Manukhin
First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
References
1. Краснопольская К.В., Штыров С.В., Мачанските О.В., Чеченова Ф.К. Исходы реконструктивно-пластических операций при трубно-перито-неальной форме бесплодия. Проблемы репродукции. 2001, 3: 12-5.
2. Кулаков В.И., Корнеева И.Е. Современные подходы к диагностике и лечению женского бесплодия. Акуш и гинекол. 2002. 2: 56-59.
3. Сухих ГТ., Назаренко Т.А. Бесплодный брак. Современные подходы к диагностике и лечению. М., 2010. 96-113.
4. Адамян Л.В., Гаспарян С.А. Генитальный эндометриоз. Современный взгляд на проблему. 2004. С. 228.
5. Адамян Л.В., Кулаков В. И., Андреева Е.Н. Эндометриозы. 2006. С 18
6. Баскаков В.П., Цвелев Ю.В., Кира Е.Ф. Эндометриоидная болезнь. 2002. С. 452.
7. Trinder J, CahiLL DJ. Endometriosis and infertility: the debate continues. Hum Fertil (Camb), 2002.
8. Adamyan L.V., Gasparyan S.A. Genital endometriosis. A modern view of the problem. 2004. P. 228.
9. Adamyan L.V., Kulakov V.I., Andreeva E.N. Endometriosis. 2006. P. 18.
10. Baskakov V.P., Tsvelev Y.V., Kira E.F. Endometriosis. 2002. P. 452.
11. Krasnopolskaya K.V., Shtyrov S.V., Machanskite O.V., Chechenova F.K. The outcomes of reconstructive and plastic surgery of tubal-peritoneal infertility. Problemy Reproduktsii. 2001, 3: 12-5.
12. Kulakov V.I., Korneeva I.E. Current approaches to diagnosis and treatment of femal infertility. Akush. i Gin. 2002. 2: 56-59.
13. Sukhikh G.T., Nazarenko T.A. Sterile marriage. Current approaches to diagnosis and treatment. М.: 2010. 96-113.
Review
For citations:
Karakashian NR, Manukhina EI, Gevorgyan MA, Manukhin IB. The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis. Meditsinskiy sovet = Medical Council. 2016;(2):100-101. (In Russ.) https://doi.org/10.21518/2079-701X-2016-2-100-101
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